abstract：:We report a man with a 3-year-history of a striking eruption of small, 2-3 mm diameter keratotic, crateriform papules distributed symmetrically over the lower limbs. Morphologically the individual papules closely resembled those described in acrokeratoelastoidosis (AK) of Costa and in focal acral hyperkeratosis of Dow...

journal_title：Clinical and experimental dermatology

authors： Helbling I,Tucker SC,Chalmers RJ

更新日期：2001-05-01 00:00:00

abstract：:High-dose intravenous immunoglobulin (hdIVIg) is being used increasingly for dermatological indications. Its mode of action is via a number of proposed mechanisms and it is not associated with the many side-effects of steroids and other immunosuppressive agents. The evidence for using hdIVIg in the treatment of autoim...

journal_title：Clinical and experimental dermatology

authors： Jolles S

更新日期：2001-03-01 00:00:00

abstract：:Necrobiosis lipoidica is a well recognized but comparatively rare cutaneous complication of diabetes mellitus. The aetiology is probably multifactorial with microangiopathy, immune complex formation, abnormal collagen synthesis and breakdown, and altered haemostasis all thought to play a part. Necrobiosis lipoidica of...

journal_title：Clinical and experimental dermatology

authors： Owen CM,Murphy H,Yates VM

更新日期：2001-03-01 00:00:00

abstract：:We report 20 patients who contracted cutaneous leishmaniasis in Central and South America, 18 of them in Belize. The diagnosis was confirmed by the polymerase chain reaction (PCR) in 79% of those tested; the corresponding figure for histology was 62%, touch smear 46%, and culture 11%. Results of PCR can be falsely pos...

journal_title：Clinical and experimental dermatology

authors： Palmer RA,Tran D,Hepburn NC,Ashton RE

更新日期：2001-01-01 00:00:00

abstract：:Schistosomiasis is endemic in many parts of the tropics and subtropics with an estimated 200 million people, at least, infected worldwide. The symptoms and signs of vesical and gastrointestinal forms are readily recognized but ectopic forms are rare even in endemic areas and present a greater diagnostic challenge, par...

journal_title：Clinical and experimental dermatology

authors： Leman JA,Small G,Wilks D,Tidman MJ

更新日期：2001-01-01 00:00:00

abstract：:Cryosurgery is an alternative treatment option to surgical excision for lentigo maligna. Clinical evidence of recurrence is usually characterized by repigmentation at the treated site. We report two patients who developed amelanotic malignant melanoma following cryosurgery for a pigmented lentigo maligna. These cases ...

journal_title：Clinical and experimental dermatology

authors： McKenna DB,Cooper EJ,Kavanagh GM,Davie RM,McLaren KM,Tidman MJ

更新日期：2000-11-01 00:00:00

abstract：:Despite the negative effects of androgenetic alopecia (AGA), no standardized health-related quality of life (HRQOL) questionnaire which is both specific to women and suitable for use in clinical trials currently exists. A questionnaire to assess HRQOL in women with AGA, the Women's Androgenetic Alopecia Quality of Lif...

journal_title：Clinical and experimental dermatology

authors： Dolte KS,Girman CJ,Hartmaier S,Roberts J,Bergfeld W,Waldstreicher J

更新日期：2000-11-01 00:00:00

abstract：:Like many other cancers, melanoma has a significant genetic basis. However, its genetic pathways may involve multiple genes with probable interactions with sun exposure. Germline mutations in p16 or CDKN2A are found in a significant percentage of relatively rare melanoma families but p16 mutations are uncommon in spor...

journal_title：Clinical and experimental dermatology

authors： Bataille V

更新日期：2000-09-01 00:00:00

abstract：:Incipient osteomalacia developed in a Pakistani patient living in the UK after strict sunlight avoidance forming part of the management of the photosensitivity disorder, chronic actinic dermatitis. The patient's skin type and diet, which included calcium-binding phytates in chappattis, had increased his risk of the co...

journal_title：Clinical and experimental dermatology

authors： Kapur N,Creamer D,Hawk J

更新日期：2000-07-01 00:00:00

abstract：:Telangiectatic leg veins (TLV) are experienced by millions of women and men. As they cause significant cosmetic embarrassment, many women seek effective treatment. Options include sclerotherapy and treatment with different lasers. We investigated the safety and efficacy of an 810-nm diode laser in the treatment of TLV...

journal_title：Clinical and experimental dermatology

authors： Varma S,Lanigan SW

更新日期：2000-07-01 00:00:00

abstract：:It is only in the past 10 years that the allergenic potential of topical corticosteroids has been fully realized. This has an important impact on the management of patients with chronic eczematous eruptions. Nonhalogenated topical steroids are more frequent sensitizers than halogenated molecules. Tixocortol pivalate a...

journal_title：Clinical and experimental dermatology

authors： English JS

更新日期：2000-06-01 00:00:00

abstract：:Acne fulminans is characterized by the sudden onset of a severe, ulcerative acne associated with systemic features. Response to traditional acne therapies is poor. We have recognized a subset of patients with acne of a severity comparable to that of acne fulminans but with the absence of systemic involvement; we sugge...

journal_title：Clinical and experimental dermatology

authors： Thomson KF,Cunliffe WJ

更新日期：2000-06-01 00:00:00

abstract：:Recent studies suggest that histamine H2-receptor antagonists may be useful in the treatment of urticaria. This study was conducted to determine whether famotidine, a H2 antagonist, is effective in the treatment of acute urticaria and compare its effect with that of the H1 antagonist diphenhydramine. In this prospecti...

journal_title：Clinical and experimental dermatology

authors： Watson NT,Weiss EL,Harter PM

更新日期：2000-05-01 00:00:00

abstract：:We present a case of paraneoplastic pemphigus associated with Castleman's disease. Our patient had stomatitis and vulvar erosions followed by a cutaneous polymorphous eruption. Investigations for neoplasia disclosed a Castleman's tumour suggesting the diagnosis of paraneoplastic pemphigus. The diagnosis was supported ...

journal_title：Clinical and experimental dermatology

authors： Caneppele S,Picart N,Bayle-Lebey P,Paul J,Irsutti M,Oksman F,Joly P,Bazex J

更新日期：2000-05-01 00:00:00

abstract：:Renal itch is localized or generalized itch, affecting patients with chronic renal failure, where there is no primary skin disease and no systemic or psychological dysfunction that might cause pruritus. It does not result from raised serum urea levels. The prevalence of renal itch has increased with the growing popula...

journal_title：Clinical and experimental dermatology

authors： Murphy M,Carmichael AJ

更新日期：2000-03-01 00:00:00

abstract：:Juvenile colloid milium is an extremely rare skin condition with an onset prior to puberty; it can be distinguished histologically from the adult form. We report a case of juvenile colloid milium associated with ligneous conjunctivitis and gingival deposits of an amyloid-like homogenous eosinophilic material. We hypot...

journal_title：Clinical and experimental dermatology

authors： Chowdhury MM,Blackford S,Williams S

更新日期：2000-03-01 00:00:00

abstract：:Although surgery may be curative in early malignant melanoma, its effect on survival lessens with each succeeding stage of the disease. A wide variety of immunological strategies have therefore been used to improve the prognosis of patients with malignant melanoma, but adjuvant therapy with interferon (IFN)-alpha is t...

journal_title：Clinical and experimental dermatology

authors： Russell-Jones R

更新日期：2000-01-01 00:00:00

abstract：:We describe a combined cutaneous hamartoma in a 57-year-old man, which comprised a vellus hair cyst, an epidermoid cyst and an intradermal melanocytic naevus in a single facial tumour. The vellus hair cyst was filled with keratinous material with unusual slit-like lacunae. While numerous cases of epidermoid cyst have ...

journal_title：Clinical and experimental dermatology

authors： Tsuruta D,Nakagawa K,Taniguchi S,Kobayashi H,Hamada T,Ishii M

更新日期：2000-01-01 00:00:00

abstract：:A retrospective study was made of the incidence of cutaneous melanoma among the population of the district of Rijeka (Croatia) during the period 1977-96. A total of 397 patients with cutaneous melanoma was documented during this period. Over the 20-year period the incidence of the tumour increased, the mean annual rat...

journal_title：Clinical and experimental dermatology

authors： Zamolo G,Gruber F,Jonjić A,Cabrijan L,Palle M,Grubisić-Greblo H

更新日期：2000-01-01 00:00:00

abstract：:IgA pemphigus is rare but may be underdiagnosed. We describe two cases, a 50-year-old female with a pustular eruption resembling subcorneal pustular dermatosis and a 55-year-old male with a pruritic vesiculopustular eruption simulating dermatitis herpetiformis. They illustrate the clinical heterogeneity of IgA pemphig...

journal_title：Clinical and experimental dermatology

authors： Harman KE,Holmes G,Bhogal BS,McFadden J,Black MM

更新日期：1999-11-01 00:00:00

abstract：:Guadeloupe is a French Caribbean island, with a population of mainly African ancestry, and a high standard of living. We recorded the dermatological diagnoses in 5000 new patients attending dermatologists. The main diagnoses were acne (16.4%), superficial mycoses (12.8%), and eczema (10.5%). Diseases considered to be ...

journal_title：Clinical and experimental dermatology

authors： Mahé A,Mancel E

更新日期：1999-09-01 00:00:00

abstract：:Pruritic folliculitis (PF) is one of the specific dermatoses of pregnancy the aetiology of which remains unknown. Several theories have been proposed, and the most commonly accepted is that it represents a hormonally induced acne, as seen in patients taking progestogenic steroids. This theory led to the proposition th...

journal_title：Clinical and experimental dermatology

authors： Vaughan Jones SA,Hern S,Black MM

更新日期：1999-09-01 00:00:00

abstract：:Myiasis is a condition resulting from the invasion of tissues or organs of man or animals by the larvae of dipterous flies. The distribution of myiasis is worldwide, with more cases being reported from tropical, subtropical, and warm temperate areas. The various forms of myiasis may be classified from an entomological...

journal_title：Clinical and experimental dermatology

authors： Delir S,Handjani F,Emad M,Ardehali S

更新日期：1999-07-01 00:00:00

abstract：:The two photodermatoses, polymorphic light eruption (PLE) and chronic actinic dermatitis (CAD), are characterized by lymphocyte-rich inflammatory infiltrates, the pathogeneses of which are not fully understood. We have therefore studied suction blister fluid (SBF) samples from patients with these conditions before and...

journal_title：Clinical and experimental dermatology

authors： Norris P,Bacon K,Bird C,Hawk J,Camp R

更新日期：1999-07-01 00:00:00

abstract：:Although pellagra is a recognized complication of isoniazid therapy, the diagnosis may be overlooked or delayed--sometimes with life-threatening consequences. We report a case of isoniazid-induced pellagra which occurred despite pyridoxine supplementation. Drug withdrawal and supplementation with niacin led to a rapid...

journal_title：Clinical and experimental dermatology

authors： Darvay A,Basarab T,McGregor JM,Russell-Jones R

更新日期：1999-05-01 00:00:00

abstract：:A 71-year-old woman with vitiligo developed multiple actinic keratoses only on the vitiligo skin of sun-exposed areas. She had worked outdoors as a farmer for a long period. Although actinic skin cancers arising on vitiligo skin have rarely been reported, the present case demonstrates that vitiligo skin is more suscep...

journal_title：Clinical and experimental dermatology

authors： Yashiro K,Nakagawa T,Takaiwa T,Inai M

更新日期：1999-05-01 00:00:00

abstract：:Granuloma annulare and localized morphoea are both well described in the dermatological literature. We now present two patients with both of these diseases, a comorbidity rarely described. A possible pathogenic relationship is discussed. ...

journal_title：Clinical and experimental dermatology

authors： Ben-Amitai D,Hodak E,Lapidoth M,David M

更新日期：1999-03-01 00:00:00

abstract：:Mohs' surgery for basal cell carcinoma (BCC) is widely recommended by dermatologists as first line surgical therapy for recurrent or ill-defined skin tumours. The technique assumes that BCC spread by contiguous growth and that all tumour cells have to be removed. Advocates claim that Mohs' surgery provides a better ch...

journal_title：Clinical and experimental dermatology

authors： Lawrence CM

更新日期：1999-03-01 00:00:00

abstract：:We report the cases of two patients who developed generalized pustular psoriasis on the withdrawal of oral Cyclosporin treatment for persistent palmoplantar pustulosis. This complication does not appear to have been reported previously. ...

journal_title：Clinical and experimental dermatology

authors： De Silva BD,Benton EC,Tidman MJ

更新日期：1999-01-01 00:00:00

abstract：:We report the case of a 30-year-old patient who developed scombrotoxic fish poisoning after eating cooked fresh tuna. Symptoms included a bright red rash, tightness of the chest, palpitations, anxiety, mild headache and dizziness, all of which resolved spontaneously within 2-3 h. Such poisoning results from the consum...

journal_title：Clinical and experimental dermatology

authors： Sabroe RA,Kobza Black A

更新日期：1998-11-01 00:00:00

abstract：:The use of an aqueous solution of 0.5% topical glycopyrollate was effective in the treatment of hyperhidrosis of the scalp and forehead after other treatments had proved ineffective; this appears to be the first report of its use in this condition. ...

journal_title：Clinical and experimental dermatology

authors： Seukeran DC,Highet AS

更新日期：1998-09-01 00:00:00

abstract：:The clinical and histological effects of retinyl propionate cream (a retinyl ester) on extrinsic skin ageing (photo-ageing) in man were assessed in a double-blind randomized placebo-controlled study of 80 subjects, individual parameters of this being assessed for each treatment site (face, dorsal right forearm and han...

journal_title：Clinical and experimental dermatology

authors： Green C,Orchard G,Cerio R,Hawk JL

更新日期：1998-07-01 00:00:00

abstract：:Carcinoma of the prostate gland is the second most frequent malignancy in males, accounting for 17% of cancer in men; between a third and one-half of these patients will have distant metastases at onset, but rarely cutaneous. We now report a case of prostatic adenocarcinoma with such metastases involving the right nip...

journal_title：Clinical and experimental dermatology

authors： Marcoval J,Moreno A,Jucglà A,Servitje O,Peyrí J

更新日期：1998-05-01 00:00:00

abstract：:Hydroa vacciniforme (HV) is a rare photodermatosis first described by Bazin in the mid-nineteenth century. It typically presents in childhood and resolves during adolescence. Rarely, however, symptoms may persist into adult life.2,3 We now describe a patient with this condition presenting unusually for the first time ...

journal_title：Clinical and experimental dermatology

authors： Blackwell V,McGregor JM,Hawk JL

更新日期：1998-03-01 00:00:00

abstract：:A 23-year-old woman presented with a 10 year history of excessive sweating (hyperhidrosis), mostly in the axillae, and to a lesser extent the groin and hands. Initial treatment with a sedative antihistamine and topical Driclor (aluminium chloride hexahydrate in 2% alcohol) for 14 weeks resulted in no improvement. Axil...

journal_title：Clinical and experimental dermatology

authors： Payne CM,Doe PT

更新日期：1998-01-01 00:00:00

abstract：:We report a patient with purely cutaneous Rosai-Dorfman disease (RDD) who presented with a solitary, asymptomatic plaque on the back of her left thigh, with characteristic, large histiocytoid cells exhibiting emperipolesis histologically. Cutaneous lesions occur in 27% of patients with lymph node involvement in RDD ho...

journal_title：Clinical and experimental dermatology

authors： Child FJ,Fuller LC,Salisbury J,Higgins EM

更新日期：1998-01-01 00:00:00

abstract：:A case of pure non-epidermotropic cutaneous lymphoma in a human immunodeficiency virus-infected patient is reported following a viral opportunistic infection [cytomegalovirus (CMV) hepatitis]. The lymphoid infiltrate was Epstein-Barr virus and CMV negative with a CD30-positive T-cell phenotype. Molecular analysis demo...

journal_title：Clinical and experimental dermatology

authors： Viraben R,Brousset P,Aquilina C,Lamant L

更新日期：1997-11-01 00:00:00

abstract：:We report a case of toxic pustuloderma secondary to thalidomide in a patient with severe nodular prurigo. To our knowledge this is the first reported case. With the increasing use of thalidomide for a variety of dermatological conditions it is clearly important that this rare side-effect now be recognised. ...

journal_title：Clinical and experimental dermatology

authors： Darvay A,Basarab T,Russell-Jones R

更新日期：1997-11-01 00:00:00

abstract：:We describe the results of a single-centre, double-blind, vehicle-controlled, parallel group study on the quantitative effects of 2% fusidic acid lotion (Fucidin lotion) in facial acne vulgaris. The trial was completed by 52 patients aged 15-25 years with mild to moderate acne who had been randomized to either Fucidin...

journal_title：Clinical and experimental dermatology

authors： Sommer S,Bojar R,Cunliffe WJ,Holland D,Holland KT,Naags H

更新日期：1997-09-01 00:00:00

abstract：:We describe a patient with intermittent unilateral hyperhidrosis localized to the left hand only. Histology confirmed the presence of an eccrine naevus. ...

journal_title：Clinical and experimental dermatology

authors： Parslew R,Lewis-Jones MS

更新日期：1997-09-01 00:00:00